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Mahmoudi, Morteza, Monopoli, Marco P., Rezaei, Meisam, Lynch, Iseult, Bertoli, Filippo, McManus, Jennifer and Dawson, Kenneth A. (2013) The Protein Corona Mediates the Impact of Nanomaterials and Slows Amyloid Beta Fibrillation. ChemBioChem, 14 (5). pp. 568-572. ISSN 1439-4227
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Abstract
Put your coat on: It is well recognized that the surfaces of nanomaterials in biological media are covered by various biomolecules (e.g., proteins). A) The protein corona creates a shell over different nanomaterials, regardless of their physicochemical properties (e.g., composition and shape), resulting in reduced levels of amyloid beta fibril formation. B) Pristine nanomaterials might have acceleratory effects on the fibrillation of amyloid beta.
| Item Type: | Article |
|---|---|
| Keywords: | Protein Corona; Nanomaterials; Amyloid Beta Fibrillation; |
| Academic Unit: | Faculty of Science and Engineering > Chemistry |
| Item ID: | 7757 |
| Identification Number: | 10.1002/cbic.201300007 |
| Depositing User: | Jennifer McManus |
| Date Deposited: | 13 Jan 2017 17:01 |
| Journal or Publication Title: | ChemBioChem |
| Publisher: | Wiley |
| Refereed: | Yes |
| Funders: | Higher Education Aithority (HEA), ESF EpitopeMap RNP, EU FP7 Small Collaborative project NeuroNano, Science Foundation Ireland (SFI) |
| Related URLs: | |
| URI: | https://mu.eprints-hosting.org/id/eprint/7757 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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