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Ryan, Gary J., Elmes, Robert B.P., Quinn, Susan J. and Gunnlaugsson, Thorfinnur (2012) Synthesis and photophysical evaluations of fluorescent quaternary bipyridyl-1,8-naphthalimide conjugates as nucleic acid targeting agents. Supramolecular Chemistry, 24 (3). pp. 175-188. ISSN 1061-0278
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Abstract
A family of organic molecules containing the DNA intercalating chromophores, 4-nitro- and
4-amino 1,8-naphthalamide, conjugated to a diquat derivative by an ‘orthogonal’ phenyl spacer have
been prepared, and characterized. Their binding interactions with double-stranded DNA was studied by
a variety of spectroscopic techniques. These charged organic compounds are found to exhibit excellent
binding affinities to DNA with binding constants comparable to those exhibited by metal complexes.
| Item Type: | Article |
|---|---|
| Additional Information: | This is the preprint version of the published article, which is available at DOI: 10.1080/10610278.2011.638381 |
| Keywords: | DNA probes; naphthalimide; fluorescence; sensors; supramolecular systems; |
| Academic Unit: | Faculty of Science and Engineering > Chemistry |
| Item ID: | 6992 |
| Identification Number: | 10.1080/10610278.2011.638381 |
| Depositing User: | Robert Elmes |
| Date Deposited: | 26 Feb 2016 16:56 |
| Journal or Publication Title: | Supramolecular Chemistry |
| Publisher: | Taylor & Francis |
| Refereed: | Yes |
| Funders: | Science Foundation Ireland (SFI), Irish Research Council for Science Engineering and Technology (IRCSET) |
| Related URLs: | |
| URI: | https://mu.eprints-hosting.org/id/eprint/6992 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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