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    Association between circadian rhythms, sleep and cognitive impairment in healthy older adults: an actigraphic study


    Cochrane, Andy, Robertson, Ian H. and Coogan, Andrew (2012) Association between circadian rhythms, sleep and cognitive impairment in healthy older adults: an actigraphic study. Journal of Neural Transmission, 119. pp. 1233-1239. ISSN 0300-9564

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    Abstract

    There is increasing evidence for the relationship between circadian rhythm disturbance and cognitive decline in the older adult. This study measured circadian activity rhythms in a small group of healthy community-dwelling older adults (n = 26). Each participant completed a battery of neuropsychological tests and completed sleep diaries and 6 days of actigraphy. Ten participants were identified as having very early signs of cognitive decline as indicated by their performance on the memory tests. Results showed minimal differences on the sleep/activity and circadian parameters across the two groups (declined vs. intact), although there was a significant difference in the acrophase between the declined and intact groups. These findings, although exploratory, suggest that very subtle changes in circadian rhythm may be detected in older adults showing pre-clinical changes in cognitive performance.
    Item Type: Article
    Additional Information: The definitive version of this article is available at DOI: 10.1007/s00702-012-0802-2
    Keywords: Sleep–wake; Circadian; Actigraphy; Older adults; Cognition;
    Academic Unit: Faculty of Science and Engineering > Psychology
    Item ID: 5977
    Identification Number: 10.1007/s00702-012-0802-2
    Depositing User: Andy Cochrane
    Date Deposited: 23 Mar 2015 15:55
    Journal or Publication Title: Journal of Neural Transmission
    Publisher: Springer Verlag
    Refereed: Yes
    Related URLs:
    URI: https://mu.eprints-hosting.org/id/eprint/5977
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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