Leamy, Darren J., Ward, Tomas E. and Kocijan, Jus (2010) Using Gaussian Process Models for Near-Infrared Spectroscopy Data Interpolation. In: 7th IASTED International Conference, Biomedical Engineering ( BioMED 2010 ), February 17 - 19 , 2010 , Innsbruck, Austria .
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Abstract
Gaussian Process (GP) model interpolation is used
extensively in geostatistics. We investigated the effectiveness
of using GP model interpolation to generate
maps of cortical activity as measured by Near Infrared
Spectroscopy (NIRS). GP model interpolation also produces
a variability map, which indicates the reliability of
the interpolated data. For NIRS, cortical hemodynamic
activity is spatially sampled. When generating cortical
activity maps, the data must be interpolated. Popular NIRS
imaging software HomER uses Photon Migration Imaging
(PMI) and Diffuse Optical Imaging (DOI) techniques
based on models of light behaviour to generate activity
maps. Very few non-parametric methods of NIRS imaging
exist and none of them indicate the reliability of the interpolated
data. Our GP model interpolation algorithm and
HomER produced activity maps based on data generated
from typical functional NIRS responses. Image results
in HomER were taken as the bench mark as the images
produced are commonly considered to be representative of
the true underlying hemodynamic spatial response. The
output from the GP approach was then compared to these
on a qualitative basis. The GP model interpolation appears
to produce less structured image maps of hemodynamic
activity compared to those produced by HomER, however
a broadly similar spatial response is compelling evidence
of the utility of GP models for such applications. The additional
generation of a variability map which is produced
by the GP method may have some utility for functional
NIRS as such information is not explicitly available from
standard approaches. GP model interpolation can produce
spatial activity maps from coarsely sampled NIRS data
sets without any knowledge of the system being modelled.
While the images produced do not appear to have the
same feature resolution as photonic model-based methods
the technique is worthy of further investigation due to its
relative simplicity and, most intriguingly, its generation
of ancillary information in the form of the variability
map. This additional data may have some utility in NIRS
optode design or perhaps it may have application as
additional input for response classification purposes. This
GP technique may also be of use where model information
is inadequate for DOI techniques.
Item Type: | Conference or Workshop Item (Paper) |
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Keywords: | Optical Imaging; Biomedical Signal Processing; Near- Infrared Spectroscopy; Gaussian process models; |
Academic Unit: | Faculty of Science and Engineering > Electronic Engineering |
Item ID: | 3861 |
Depositing User: | Dr Tomas Ward |
Date Deposited: | 14 Sep 2012 14:39 |
Refereed: | Yes |
URI: | https://mu.eprints-hosting.org/id/eprint/3861 |
Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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