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    The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity


    Thomson, Emma C., Rosen, Laura E., Shepherd, James G., Spreafico, Roberto, da Silva Filipe, Ana, Wojcechowskyj, Jason A., Davis, Chris, Piccoli, Luca, Pascall, David J., Dillen, Josh, Lytras, Spyros, Czudnochowski, Nadine, Shah, Rajiv, Meury, Marcel, Jesudason, Natasha, De Marco, Anna, Li, Kathy, Bassi, Jessica, O’Toole, Aine, Pinto, Dora, Colquhoun, Rachel M., Culap, Katja, Jackson, Ben, Zatta, Fabrizia, Rambaut, Andrew, Jaconi, Stefano, Sreenu, Vattipally B., Nix, Jay, Jarrett, Ruth F., Beltramello, Martina, Nomikou, Kyriaki, Pizzuto, Matteo, Tong, Lily, Cameroni, Elisabetta, Johnson, Natasha, Wickenhagen, Arthur, Ceschi, Alessandro, Mair, Daniel, Ferrari, Paolo, Smollett, Katherine, Sallusto, Federica, Carmichael, Stephen, Garzoni, Christian, Nichols, Jenna, Galli, Massimo, Hughes, Joseph, Riva, Agostino, Ho, Antonia, Semple, Malcolm G., Openshaw, Peter J.M., Baillie, J. Kenneth, Rihn, Suzannah J., Lycett, Samantha J., Virgin, Herbert W., Telenti, Amalio, Corti, Davide, Robertson, David L., Snell, Gyorgy and Fadda, Elisa (2020) The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity. bioRxiv.

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    Item Type: Article
    Additional Information: Cite as: Thomson, E.C., Rosen, L.E., Shepherd, J.G., Spreafico, R., Ana Da Silva Filipe, Wojcechowskyj, J.A., Davis, C., Piccoli, L., Pascall, D.J., Dillen, J., Lytras, S., Czudnochowski, N., Shah, R., Meury, M., Jesudason, N., De Marco, A., Li, K., Bassi, J., O’toole, A., Pinto, D., Colquhoun, R.M., Culap, K., Jackson, B., Zatta, F., Rambaut, A., Jaconi, S., Sreenu, V.B., Nix, J., Jarrett, R.F., Beltramello, M., Nomikou, K., Pizzuto, M., Tong, L., Cameroni, E., Johnson, N., Wickenhagen, A., Ceschi, A., Mair, D., Ferrari, P., Smollett, K., Sallusto, F., Carmichael, S., Garzoni, C., Nichols, J., Galli, M., Hughes, J., Riva, A., Ho, A., Semple, M.G., Openshaw, P.J., Baillie, J.K., Investigators, T.I., The Covid-19 Genomics Uk (Cog-Uk) Consortium, Rihn, S.J., Lycett, S.J., Virgin, H.W., Telenti, A., Corti, D., Robertson, D.L. & Snell, G. 2020, The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity, Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
    Keywords: Biotechnology; Clinical trials; Epidemiology; Fitness; Immunity; Monoclonal antibodies; Mutation; Severe acute respiratory syndrome coronavirus 2; Vaccines; Virulence;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Faculty of Science and Engineering > Research Institutes > Hamilton Institute
    Faculty of Science and Engineering > Research Institutes > Human Health Institute
    Item ID: 17388
    Identification Number: 10.1101/2020.11.04.355842
    Depositing User: Elisa Fadda
    Date Deposited: 06 Jul 2023 14:42
    Journal or Publication Title: bioRxiv
    Publisher: Cold Spring Harbor Laboratory Press
    Refereed: Yes
    Related URLs:
    URI: https://mu.eprints-hosting.org/id/eprint/17388
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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