Bondopadhyay, Upasana, Díaz-Orueta, Unai and Coogan, Andrew (2021) The Role of the Circadian System in Attention Deficit Hyperactivity Disorder. Advances in Experimental Medicine and Biology 1344, 1344. pp. 113-127. ISSN 0065-2598
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Abstract
Attention deficit hyperactivity disorder
(ADHD) is a common neurodevelopmental
condition characterised by the core symptoms
of inattention, impulsivity and hyperactivity.
Similar to many other neuropsychiatric
conditions, ADHD is associated with very
high levels of sleep disturbance. However, it
is not clear whether such sleep disturbances
are precursors to, or symptoms of, ADHD.
Neither is it clear through which mechanisms
sleep and ADHD are linked. One possible link
is via modulation of circadian rhythms. In this
chapter we overview the evidence that ADHD
is associated with alterations in circadian processes, manifesting as later chronotype and
delayed sleep phase in ADHD, and examine
some mechanisms that may lead to such
changes. We also interrogate how the circadian clock may be a substrate for therapeutic
intervention in ADHD (chronotherapy) and
highlight important new questions to be
addressed to move the field forward.
Item Type: | Article |
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Additional Information: | Cite as: Bondopadhyay, U., Diaz-Orueta, U. and Coogan, A.N., 2021. The role of the circadian system in attention deficit hyperactivity disorder. Circadian Clock in Brain Health and Disease, pp.113-127. |
Keywords: | ADHD; |
Academic Unit: | Assisting Living & Learning,ALL institute Faculty of Science and Engineering > Psychology |
Item ID: | 16793 |
Identification Number: | 10.1007/978-3-030-81147-1_7 |
Depositing User: | Unai Diaz-Orueta |
Date Deposited: | 20 Dec 2022 15:35 |
Journal or Publication Title: | Advances in Experimental Medicine and Biology 1344 |
Refereed: | Yes |
URI: | https://mu.eprints-hosting.org/id/eprint/16793 |
Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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