This study assesses the seasonal forecast skill of river flow persistence in 46 catchments representing a range of hydrogeological conditions across Ireland. Skill is evaluated against a climatology benchmark forecast and by examining correlations between predicted and observed flow anomalies. Forecasts perform best when initialized in drier summer months, 87% of which show greater skill relative to the benchmark at a 1-month horizon. Such skill declines as forecast horizon increases due to the longer time a catchment has to “forget” initial anomalous flow conditions and/or to be impacted by “new” events. Skill is related to physical catchment descriptors such as the baseflow index (correlation ρ = 0.86) and is greatest in permeable high-storage catchments. The distinct seasonal and spatial variations in persistence skill allow us to pinpoint when and where this method can provide a useful benchmark in the future development of more complex seasonal hydrological forecasting approaches in Ireland.