5G technology is expected to enable many innovative applications in different verticals. These applications have heterogeneous performance requirements (e.g., high data rate, low latency, high reliability, and high availability). In order to meet these requirements, 5G networks endorse network flexibility through the deployment of new emerging technologies, mainly network slicing and mobile edge computing. This article introduces a distributed blockchain-enabled network slicing (DBNS) framework that enables service and resource providers to dynamically lease resources to ensure high performance for their end-to-end services. The key component of our framework is global service provisioning, which provides admission control for incoming service requests along with dynamic resource assignment by means of a blockchain-based bidding system. The goal is to improve users’ experience with diverse services and reduce providers’ capital and operational expenditure.