We survey some work concerned with small universal Turing machines, cellular automata, tag systems, and other simple models of computation. For example, it has been an open question for some time as to whether the smallest known universal Turing machines of Minsky, Rogozhin, Baiocchi and Kudlek are efficient (polynomial time) simulators of Turing machines. These are some of the most intuitively simple computational devices and previously the best known simulations were exponentially slow. We discuss recent work that shows that these machines are indeed efficient simulators. As a related result, we also find that Rule 110, a well-known elementary cellular automaton, is also efficiently universal. We also review a large number of old and new universal program size results, including new small universal Turing machines and new weakly, and semi-weakly, universal Turing machines. We then discuss some ideas for future work arising out of these, and other, results.